Loss of basal feet on Odf2 deletion perturbs polarization of basal bodies
نویسندگان
چکیده
منابع مشابه
Coordinated Ciliary Beating Requires Odf2-Mediated Polarization of Basal Bodies via Basal Feet
Coordinated beating of cilia in the trachea generates a directional flow of mucus required to clear the airways. Each cilium originates from a barrel-shaped basal body, from the side of which protrudes a structure known as the basal foot. We generated mice in which exons 6 and 7 of Odf2, encoding a basal body and centrosome-associated protein Odf2/cenexin, are disrupted. Although Odf2(ΔEx6,7/ΔE...
متن کاملBasal bodies
La rete nervosa diffusa [Golgi] nello strato dei granuli del cervelletto. Activité électrique du cortex cérébral dans les états de sommeil et de veille chez le chat. C. Azione di alcune sostanze chimiche sulle zone eccitabili della corteccia cerebrale del cane. The functional analysis of the cortical centres by means of local chemical stimulation. Q. One or many arousal systems? Reflections on ...
متن کاملTwo appendages homologous between basal bodies and centrioles are formed using distinct Odf2 domains
Ciliogenesis is regulated by context-dependent cellular cues, including some transduced through appendage-like structures on ciliary basal bodies called transition fibers and basal feet. However, the molecular basis for this regulation is not fully understood. The Odf2 gene product, ODF2/cenexin, is essential for both ciliogenesis and the formation of the distal and subdistal appendages on cent...
متن کاملBasal Bodies of Bacterial In
This paper investigates further the question of whether the flagella of Proteus mirabilis emerge from basal bodies. The bacteria were grown to the stage of swarmer differentiation, treated lightly with penicillin, and then shocked osmotically. As a result of this treatment, much of the cytoplasmic content and also part of the plasma membrane were removed from the cells. When such fragmented org...
متن کاملBasal Bodies of Bacterial In
This paper investigates further the question of whether the flagella of Proteus mirabilis emerge from basal bodies. The bacteria were grown to the stage of swarmer differentiation, treated lightly with penicillin, and then shocked osmotically. As a result of this treatment, much of the cytoplasmic content and also part of the plasma membrane were removed from the cells. When such fragmented org...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cilia
سال: 2012
ISSN: 2046-2530
DOI: 10.1186/2046-2530-1-s1-o26